Oltre alle molte novità in video, lo scopo principale del VGA 2009 era premiare i migliori titoli del 2009: eccovi quindi di seguito la lista di tutti i premi assegnati.

• Game of the Year: Uncharted 2: Among Thieves
• Studio of the Year: Rocksteady Studios
• Best Independent Game Fueld by Dew: Flower
• Best Xbox 360 Game: Left 4 Dead 2
• Best PS3 Game: Uncharted 2: Among Thieves
• Best Wii Game: New Super Mario Bros. Wii
• Best PC Game: Dragon Age: Origins
• Best Handheld Game: Grand Theft Auto: Chinatown Wars
• Best Shooter: Call of Duty: Modern Warfare 2
• Best Fighting Game: Street Fighter IV
• Best Action Adventure Game: Assassin's Creed II
• Best RPG: Dragon Age: Origins
• Best Multiplayer Game: Call of Duty: Modern Warfare 2
• Best Individual Sports Game: UFC 2009 Undisputed
• Best Team Sports Game: NHL 10
• Best Driving Game: Forza Motorsport 3
• Best Music Game: The Beatles: Rock Band
• Best Soundtrack: DJ Hero
• Best Original Score: Halo 3: ODST
• Best Graphics: Uncharted 2: Among Thieves
• Best Game Based On A Movie/TV Show: South Park Let's Go Tower Defense Play!
• Best Performance By A Human Female: Megan Fox as Mikaela Banes in Transformers: Revenge of the Fallen
• Best Performance By A Human Male: Hugh Jackman as Wolverine in X-Men Origins: Wolverine
• Best Cast: X-Men Origins: Wolverine
• Best Voice: Jack Black for the voice of Eddie Riggs in Brütal Legend
• Best Downloadable Game: Shadow Complex
• Best DLC: Grand Theft Auto IV: The Ballad of Gay Tony
• Most Anticipated Game of 2010: God of War III